Subject code BT3761 deals with the semester VII subject syllabus from Anna University 2021 relevant to affiliated institutions. In this article, we would like to introduce the syllabus of the BT3761 – Downstream Processing in B.Tech Biotechnology and Biochemical Engineering.
We like to provide the BT3761 – Downstream Processing syllabus for students to perform well academically. This article will assist the students in getting the required syllabus for each unit with different concepts. We include expert textbooks and references for students to avoid confusion when reading books. The following links will help you to select the subject you want to read. Hope this information is useful. Don’t forget to share this information with your friends.
If you want to know more about the syllabus of B.Tech Biotechnology and Biochemical Engineering Syllabus connected to an affiliated institution’s four-year undergraduate degree program. We provide you with a detailed Year-wise, semester-wise, and Subject-wise syllabus in the following link B.Tech Biotechnology and Biochemical Engineering Syllabus Anna University Regulation 2021.
Aim Of Concept:
- To provide hands-on training in Downstream processing through simple experimentations in the laboratory. This will be a pre-requisite for project work.
- The objectives of this course is to practice the students
- To understand the nature of the end product, its concentration, stability and degree of purification required
- To design processes for the recovery and subsequent purification of target biological products.
BT3761 – Downstream Laboratory Syllabus
Experiments:
- Solid-liquid separation – centrifugation
- Solid-liquid separation – microfiltration
- Cell disruption techniques – ultrasonication or French pressure cell or Dynomill
- Precipitation – ammonium sulphite precipitation
- Ultra filtration separation
- Aqueous two-phase extraction of biologicals
- High-resolution purification – affinity chromatography
- High-resolution purification – ion exchange chromatography
- Product polishing – spray drying or freeze-drying
- Size exclusion chromatography
References:
- P.A. Belter, E.L. Cussler And Wei-Houhu – Bioseparations – Downstream Processing For Biotechnology, Wiley Interscience Pun. (1988).
- J.C. Janson And L. Ryden, (Ed.) – Protein Purification – Principles, High ResolutionMethods And Applications, VCH Pub. 1989.
- Michael R.Ladisch Bioseparations Engineering: Principles, practice and Economics, Wiley- Interscience, 1st Edition,2001.
- Product Recovery in Bioprocess Technology”. (BIOTOL – Biotechnology by Open Learning Series). Butterworth – Heinmann / Elsevier, 2004.
- Raja Ghosh “Principles of Bioseparations Engineering”. World Scientific, 2006
Related Posts On Semester – VII:
- BT3751 – Downstream Processing
- GE3791 – Human Values and Ethics
- BI3711 – Industrial Training/Internship II
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