BT3651 - Bioprocess Engineering Syllabus Regulation 2021 Anna University

Subject code BT3651 deals with the semester VI subject syllabus from Anna University 2021 relevant to affiliated institutions. In this article, we would like to introduce the syllabus of the BT3651 – Bioprocess Engineering in B.Tech Biotechnology and Biochemical Engineering.

We like to provide the BT3651 – Bioprocess Engineering syllabus for students to perform well academically. This article will assist the students in getting the required syllabus for each unit with different concepts. We include expert textbooks and references for students to avoid confusion when reading books. The following links will help you to select the subject you want to read. Hope this information is useful. Don’t forget to share this information with your friends.

If you want to know more about the syllabus of B.Tech Biotechnology and Biochemical Engineering Syllabus connected to an affiliated institution’s four-year undergraduate degree program. We provide you with a detailed Year-wise, semester-wise, and Subject-wise syllabus in the following link B.Tech Biotechnology and Biochemical Engineering Syllabus Anna University Regulation 2021.

Aim Of Concept:

  • To provide the students with the basics of bioreactor engineering.
  • To develop bioengineering skills for the production of biochemical product using integrated biochemical processes.

BT3651 – Bioprocess Engineering Syllabus

Unit I: Configuration Of Bioreactors

Ideal reactors and its characteristicsFed batch cultivation, Cell recycle cultivation, Cell recycle cultivation in waste water treatment, two stage cultivation Packed bed reactor, airlift reactor, introduction to fluidized bed reactor bubble column reactors

Unit II: Bioreactor Scale – Up

Regime analysis of bioreactor processes, oxygen mass transfer in bioreactors – microbial oxygen demands; methods for the determination of mass transfer coefficients; mass transfer correlations. Scale-up criteria for bioreactors based on oxygen transfer, power consumption and impeller tip speed.

Unit III: Bioreactor Consideration In Enzyme Systems

Analysis of film and pore diffusion effects on kinetics of immobilized enzyme reactions; formulation of dimensionless groups and calculation of effectiveness factors. Design of immobilized enzyme reactors – packed bed, fluidized bed and membrane reactors

Unit IV: Modelling And Simulation Of Bioprocesses

Study of structured models for analysis of various bioprocess – compartmental models, models of cellular energetics and metabolism, single cell models, plasmid replication and plasmid stability model. Dynamic simulation of batch, fed batch, steady and transient culture metabolism.

BT3651 - Bioprocess Engineering Syllabus Regulation 2021 Anna University

Unit V: Recombinant Cell Cultivation

Different host vector system for recombinant cell cultivation strategies and advantages. E.coli, yeast Pichia pastoris/ Saccharomyces cereviseae, Animal cell cultivation, plant cell cultivation, Insect cell cultivation. High cell density cultivation, process strategies, reactor considerations in the above system

Text Books:

  1. Michael L. Shuler, Fikret Kargi, Matthew De Lisa,.Bioprocess Engineering, 3rdEdition,Prentice Hal, 2017
  2. Pauline Doran, Bioprocess Engineering Calculation, 2nd Edition, Blackwell Scientific Publications,2012.
  3. Sarfaraz K. Niazi, Justin L. Brown, Fundamentals of Modern Bioprocessing, Taylor & Francis,2017

References:

  1. Anton Moser, “Bioprocess Technology: Kinetics and Reactors”, Springer Verlag, 2012.
  2. James E. Bailey & David F. Ollis, Biochemical Engineering Fundamentals, McGraw Hill, 1986.
  3. James M. Lee, Biochemical Engineering, PHI, USA.1992
  4. Harvey W. Blanch, Douglas S. Clark, Biochemical Engineering, CRC Press,1997

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Anna University Syllabus 2021